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Serotonin

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Serotonin is a chemical compound being produced by nerve cells

Serotonin is a chemical compound being produced by nerve cells. It is capable of sending the signal in between the nerve cells. This particular compound occurs in the digestive system. Also, it has been found in the blood platelets as well as the CNS (Central Nervous System). This chemical compound is impacting each and every part of the body. This is specifically ranging from emotions to motor skills. The serotonin chemical is considered a natural stabilizer of mood. It has also been found to reduce depression, and anxiety, heal wounds, stimulate nausea as well as maintain bone health. One of the main psychedelic compounds existing in the magic mushroom is Psilocybin. This is demonstrating the promising therapy for depression and many other cognitive disorders.

Serotonin significantly effects mood of a person

The psychedelic impacts are also believed to emerge through the stimulation of the serotonin 2A receptors with the active metabolite, psilocin. However, psychedelic therapy still remains at an experimental stage. But the clinical trials have demonstrated that Psilocybin may be an extremely impactful cure for neuropsychiatric disorders. Some of the ailments include resistant major depressive disorder (MDD), drug addictions, anxiety, and depression during cancer. The serotonin compounds are also known as the happiness or confidence molecule. The studies have demonstrated that when there occur alterations in the level of tryptophan molecules, it significantly alters the mood of a person. So, this means that when there is a reduced level of serotonin, it contributes to depression. Also, when there is an elevated level of this particular compound, it leads to a more positive and confident mood. The serotonergic hallucinations will be including the prototypical chemicals. This includes mescaline, psilocin & even LSD.
This is representing the specific class of compounds known as psychedelics. Such chemicals have been known to induce dramatic alterations in the perception, impact consciousness, and at the same time experience the self.

There is revamped interest in the application of serotonin in mental health care

The serotonin compounds are also known as the happiness or confidence molecule. The studies have demonstrated that when there occur alterations in the level of tryptophan molecules, it significantly alters the mood of a person. So, this means that when there is a reduced level of serotonin, it contributes to depression. Also, when there is an elevated level of this particular compound, it leads to a more positive and confident mood. The serotonergic hallucinations will be including the prototypical chemicals. This includes mescaline, Psilocybin & even LSD. This is representing the specific class of compounds known as psychedelics. The psychedelic compounds are undeniably emerging as a potential novel therapeutic in the field of mental health care.

The serotonin compounds can be relatively safe & truly life-altering

In the last few decades, the revamped interest in the application of serotonin in mental health care has already generated extensive work on the pharmacological as well as therapeutic action of the molecules. Due to this, the clinical application of the compounds has already begun, and soon expand. This indicates the utilization of psychedelic compounds for therapeutic purposes and may be incorporated in today’s modern society. However, despite of the burgeoning promise in the field of mental health care, psychedelic compounds have not yet been considered to be adopted in the mainstream industry. Also, its utilization is still largely condoned only in the experimental or even monitor setting. There is also the possibility that the substances can lead to impairment. Thus, it is extremely important to utilize them under supervision. However, when consumed under the guidance of a mental healthcare expert, the serotonin compounds can be relatively safe & truly life-altering.

The human brain is complex to the extent its internal wiring mechanism is least understood. Imbalances cause problems with health, but knowing about serotonin receptors has improved our understanding of control mechanisms involving cognitive emotion, memory, and sleep-wake cycle. Bright Minds team of scientists seeks to create the next generation of serotonin drugs to target specific conditions, reducing side effects and improving therapeutic action, helping patients lead a better life.

Questions Related to the Use of Psychedelic Drugs

The creation of novel chemical entities to improve first-generation psychedelic compounds like psilocybin to make specific drugs that target serotonin receptors help influence a specific neural circuit. This is not possible with other currently approved drugs such as selective serotonin reuptake inhibitors. The questions that arise to the mind are these:

1) Will psychedelic drugs be a game-changer during these COVID-19 times when mental illness is on the rise?

2) Can we use magic mushrooms for addiction, depression, and ailments such as epilepsy?

3) How safe is it for older adults to use second-generation psychedelic drugs?

4) After terminally ill patients could legally consume psychedelic drugs to treat end-of-life distress, will it become a main-stream medical treatment?

Currently approved drugs show side effects because they are not specific to a particular receptor type. Also, the patients do not respond well to the treatment.

Controlling Disease Through The Receptor Circuit

Bright Minds Biosciences

Serotonin receptors co-localize with GABAergic, cholinergic, and glutamatergic neurons helping serotonin receptor agonists influence the major neurotransmitter systems. They can influence the progress of disease a lot. The Bright Minds Bio team has engineered superior molecules with improvements to the current state of the existence of molecules that improve targeting specific serotonin receptors in the brain.

The Action of Serotonin Receptors

The team comprises top scientists with at least 25 years of experience in drug development. Patients with chronic pain suffer because of insufficient control of the functional connectivity of brain circuits. Existing approved medications solve little. The key action on the 5-HA2A serotonin receptor helps solve major depressive disorder symptoms. But Psilocybin has a potent effect on 5-HA2A/C and 5-HA2C serotonin receptors.

Use Effective Medicine Through Targeting

There are 14 distinct subtypes of Serotonin (5-HT) receptors distributed throughout the central nervous system, including the spinal cord. Drug development based on translational science has helped us develop an extensive library of proprietary medicine to target 5-HA2A, 5-HA2A/C, and 5-HA2C serotonin receptors. Because of the important role 5-HA2C plays in impulse control, the team is developing compounds that will help the treatment of binge eating disorders, smoking, cocaine abuse, and opiate abuse. We target patients with major depressive disorder (MDD) resistant to SSRIs who need electric shock treatment or nasal ketamine treatment with Biosciences drugs without side effects like worsening impulsivity, weight gain, or worsening sleep. Atypical antipsychotics used to treat HIDA symptoms have a modest effect.

Opt For Dependable Treatment Methods

Precision is the key, and intelligent drug design based on advanced molecular modeling helps the team select compounds showing the best activity profile. You can avoid the use of unapproved psychedelic drugs and opiates to treat pain. We have made it possible to treat a wide range of disorders helping patients lead a healthy life.